APOE
HGNC ↗3 article(s) in the watch · Pharmacogenomics
APOE is involved in lipid metabolism. The ε4 allele is the main common genetic risk factor for Alzheimer disease and modulates the response to some anti-amyloid therapies; it is not a Mendelian determinant.
Curated publications
APOE genotype and the effect of statins on lipid outcomes: A meta-analysis
Lipid response to statins by APOE genotype — meta-analysis
APOE-guided lecanemab dosing dissociates ARIA-E from ARIA-H: The K-ROAD study.
Early Alzheimer disease
Clinical Outcomes of an ApoE Genotype-Guided Lipid-Lowering Strategy in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention.
Acute coronary syndrome after percutaneous coronary intervention
Frequently asked questions
How many Geno'X publications cover the APOE gene?+
3 publication(s) on APOE have been selected, summarised and scored by Geno'X on a public grading grid (domains: Pharmacogenomics).