CEBPA

2 article(s) in the watch · Constitutional genetics · Cancer genetics

CEBPA encodes a transcription factor of myeloid differentiation. Germline variants predispose to familial acute myeloid leukaemia.

InheritanceAutosomal dominant

Clinical spectrumAcute myeloid leukaemia (familial form)

ManagementHaematological surveillance; genetic counselling before related stem-cell donation.

Curated publications

Location matters: topography of germline CEBPA variants in familial acute myeloid leukaemia.

Familial acute myeloid leukaemia with germline CEBPA variants

Location matters: topography of germline CEBPA variants predicts variable outcomes in familial acute myeloid leukaemia-a rare disease perspective

Familial germline CEBPA acute myeloid leukemia