← Gene index
CTNNA1
HGNC ↗1 article(s) in the watch · Cancer genetics
CTNNA1 encodes alpha-E-catenin, a partner of E-cadherin. Pathogenic variants predispose to hereditary diffuse gastric cancer in CDH1-negative families.
InheritanceAutosomal dominant
Clinical spectrumDiffuse gastric cancer
ManagementEndoscopic surveillance; management in an oncogenetics setting.
Curated publications
Frequently asked questions
How is a CTNNA1-related condition inherited?+
Autosomal dominant
What is the clinical spectrum associated with CTNNA1?+
Diffuse gastric cancer
What is the management associated with CTNNA1?+
Endoscopic surveillance; management in an oncogenetics setting.
How many Geno'X publications cover the CTNNA1 gene?+
1 publication(s) on CTNNA1 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Cancer genetics).
