← Gene index
CYP2C9
HGNC ↗1 article(s) in the watch · Pharmacogenomics
CYP2C9 metabolises many narrow-therapeutic-index drugs: warfarin, phenytoin, NSAIDs, siponimod. Its reduced-function alleles modulate dosing and adverse-event risk (CPIC guidelines, with VKORC1 for warfarin).
PharmacogenomicsLevel APharmGKB 1A
Drugs involved: warfarin, NSAIDs, phenytoin, fluvastatin
Recommendation: CPIC level A