CYP2C9
HGNC ↗2 article(s) in the watch · Pharmacogenomics
CYP2C9 metabolises many narrow-therapeutic-index drugs: warfarin, phenytoin, NSAIDs, siponimod. Its reduced-function alleles modulate dosing and adverse-event risk (CPIC guidelines, with VKORC1 for warfarin).
Drugs involved: warfarin, NSAIDs, phenytoin, fluvastatin
Recommendation: CPIC level A
Curated publications
Drug-gene interactions and the risk of diabetic microvascular complications: A population-based cohort study
Diabetic microvascular complications — influence of drug-gene interactions on risk
The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin
Drug-drug interaction and anticoagulation
Frequently asked questions
Which drugs are affected by CYP2C9 in pharmacogenomics?+
warfarin, NSAIDs, phenytoin, fluvastatin — CPIC level A
How many Geno'X publications cover the CYP2C9 gene?+
2 publication(s) on CYP2C9 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Pharmacogenomics).
