MEN1

1 article(s) in the watch · Cancer genetics

MEN1 encodes menin, a tumour suppressor. Loss of function causes multiple endocrine neoplasia type 1.

InheritanceAutosomal dominant

Clinical spectrumHyperparathyroidism, pituitary adenomas, pancreatic NETs

ManagementRegular multi-organ biochemical and imaging surveillance.

Curated publications

A de novo MEN1 gene mutation in a 4-year-old boy with hypoglycemia: A case report and literature review

MEN1 (multiple endocrine neoplasia type 1), de novo MEN1 mutation, pediatric insulinoma at age 4