MEN1
HGNC ↗3 article(s) in the watch · Cancer genetics
MEN1 encodes menin, a tumour suppressor. Loss of function causes multiple endocrine neoplasia type 1.
Curated publications
A de novo MEN1 gene mutation in a 4-year-old boy with hypoglycemia: A case report and literature review
MEN1 (multiple endocrine neoplasia type 1), de novo MEN1 mutation, pediatric insulinoma at age 4
Association between genotype and long-term risk of reintervention and distant metastases in patients with multiple endocrine neoplasia type 1-associated duodenopancreatic neuroendocrine tumors.
Multiple endocrine neoplasia type 1: duodenopancreatic neuroendocrine tumors, reintervention and metastases according to genotype
Genetic testing considerations for hereditary duodenopancreatic neuroendocrine tumors
Hereditary duodenopancreatic neuroendocrine tumours
Frequently asked questions
How is a MEN1-related condition inherited?+
Autosomal dominant
What is the clinical spectrum associated with MEN1?+
Hyperparathyroidism, pituitary adenomas, pancreatic NETs
What is the management associated with MEN1?+
Regular multi-organ biochemical and imaging surveillance.
How many Geno'X publications cover the MEN1 gene?+
3 publication(s) on MEN1 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Cancer genetics).