MEN1

1 article(s) in the watch · Cancer genetics

MEN1 encodes menin, a tumour suppressor. Loss of function causes multiple endocrine neoplasia type 1.

InheritanceAutosomal dominant

Clinical spectrumHyperparathyroidism, pituitary adenomas, pancreatic NETs

ManagementRegular multi-organ biochemical and imaging surveillance.

Curated publications

A de novo MEN1 gene mutation in a 4-year-old boy with hypoglycemia: A case report and literature review

MEN1 (multiple endocrine neoplasia type 1), de novo MEN1 mutation, pediatric insulinoma at age 4

How is a MEN1-related condition inherited?+

Autosomal dominant

What is the clinical spectrum associated with MEN1?+

Hyperparathyroidism, pituitary adenomas, pancreatic NETs

What is the management associated with MEN1?+

Regular multi-organ biochemical and imaging surveillance.

How many Geno'X publications cover the MEN1 gene?+

1 publication(s) on MEN1 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Cancer genetics).