RB1
HGNC ↗2 article(s) in the watch · Cancer genetics
RB1 is the prototypical tumour-suppressor gene. Germline variants cause heritable retinoblastoma and a risk of second cancers.
Curated publications
Integrative Genomic Mapping and Visualization From Curated Public Datasets Reveals Germline RB1 Variant Diversity in Retinoblastoma.
Hereditary retinoblastoma (RB1 variants)
Spectrum of Germline Cytogenomic Alterations in RB1 in Mexican Patients With Retinoblastoma.
Retinoblastoma — germline RB1 cytogenomic spectrum in Mexican patients
Frequently asked questions
How is a RB1-related condition inherited?+
Autosomal dominant
What is the clinical spectrum associated with RB1?+
Retinoblastoma, osteosarcoma and other second cancers
What is the management associated with RB1?+
Early infant ophthalmological screening; second-tumour surveillance.
How many Geno'X publications cover the RB1 gene?+
2 publication(s) on RB1 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Cancer genetics).
