← Gene index
SLCO1B1
HGNC ↗1 article(s) in the watch · Pharmacogenomics
SLCO1B1 encodes the hepatic organic-anion transporter OATP1B1, involved in statin uptake. The c.521T>C (*5) variant increases the risk of statin-associated myopathy, particularly with simvastatin (CPIC guidelines).
PharmacogenomicsLevel APharmGKB 1A
Drugs involved: statins (notably simvastatin) — myopathy risk
Recommendation: CPIC level A
Curated publications
Frequently asked questions
Which drugs are affected by SLCO1B1 in pharmacogenomics?+
statins (notably simvastatin) — myopathy risk — CPIC level A
How many Geno'X publications cover the SLCO1B1 gene?+
1 publication(s) on SLCO1B1 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Pharmacogenomics).
