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VKORC1
HGNC ↗1 article(s) in the watch · Pharmacogenomics
VKORC1 is the target of vitamin-K antagonists. Together with CYP2C9, its genotype explains a substantial part of the interindividual variability in warfarin dosing and informs dosing algorithms (CPIC guidelines).
PharmacogenomicsLevel APharmGKB 1A
Drugs involved: warfarin and vitamin-K antagonists
Recommendation: CPIC level A (with CYP2C9)