Gene index

VKORC1

HGNC ↗

1 article(s) in the watch · Pharmacogenomics

VKORC1 is the target of vitamin-K antagonists. Together with CYP2C9, its genotype explains a substantial part of the interindividual variability in warfarin dosing and informs dosing algorithms (CPIC guidelines).

PharmacogenomicsLevel APharmGKB 1A

Drugs involved: warfarin and vitamin-K antagonists

Recommendation: CPIC level A (with CYP2C9)

Curated publications

Frequently asked questions

Which drugs are affected by VKORC1 in pharmacogenomics?+

warfarin and vitamin-K antagonists — CPIC level A (with CYP2C9)

How many Geno'X publications cover the VKORC1 gene?+

1 publication(s) on VKORC1 have been selected, summarised and scored by Geno'X on a public grading grid (domains: Pharmacogenomics).